49ers WR Brandon Aiyuk inactive vs. Giants

San Francisco 49ers wide receiver Brandon Aiyuk is inactive for the team's game against the New York Giants due to a shoulder injury.

San Francisco wide receiver Brandon Aiyuk will not be playing in the 49ers' home game against the New York Giants on Thursday night. Aiyuk sustained a shoulder injury during the game against the Los Angeles Rams on Sunday, but managed to make two more catches and finish with 43 yards in a road victory. Despite his strong start to the season, which earned him NFC Offensive Player of the Week honors in Week 1, Aiyuk's injury will keep him out of the upcoming game.

Another player who will be inactive for the 49ers is cornerback Ambry Thomas, who injured his knee in the game against the Rams. Thomas had started both games this season and has recorded eight tackles so far. In response to these injuries, the 49ers have activated wide receiver Chris Conley, as well as cornerbacks Tre Swilling and Shemar Jean-Charles from the practice squad to the active roster. The team has also released cornerback Anthony Brown.

Aiyuk, who was selected as the 25th overall pick in the 2020 NFL Draft out of Arizona State, has been a key player for the 49ers in his four seasons with the team. He has started in 46 out of 48 games and has accumulated 205 receptions for 2,761 yards and 20 touchdowns. Additionally, he has rushed for 117 yards and two scores in his career.

These roster changes will impact the 49ers' upcoming game against the Giants, as they will be without two key players in Aiyuk and Thomas. However, with the activation of Conley, Swilling, and Jean-Charles, the team hopes to fill the gaps and continue their success on the field. It will be interesting to see how these changes affect the outcome of the game and how the 49ers adapt to the absence of Aiyuk and Thomas.