Giants RB Saquon Barkley Inactive for Monday Night Football

New York Giants running back Saquon Barkley will miss Monday night's game against the Seattle Seahawks due to injury.

The New York Giants will be without star running back Saquon Barkley for their upcoming game against the Seattle Seahawks. Barkley has been sidelined since injuring his ankle during a game against the Arizona Cardinals on September 17. Despite participating in limited practice on Saturday, Barkley was listed as doubtful on the injury report and was not expected to play. This is a significant blow for the Giants, as Barkley leads the team in yards from scrimmage and touchdowns. In his absence, the Giants will rely on backups Matt Breida and Gary Brightwell.

In addition to Barkley, the Giants will also be without left tackle Andrew Thomas, who has a hamstring injury. Thomas will be replaced by Josh Ezeudu. On the Seahawks' side, they will be missing left tackle Charles Cross, who is inactive due to a toe injury. This is a notable absence as Cross is responsible for protecting quarterback Geno Smith's blind side. The Seahawks will also be without backup cornerbacks Coby Bryant, Tre Brown, and Artie Burns.

However, the Seahawks will have safety Jamal Adams back in action. Adams has not played since suffering a season-ending torn quad tendon in the 2022 season opener. This game will also mark Adams' return to MetLife Stadium, where he previously played for the New York Jets.

Overall, both teams will have to make adjustments due to key injuries. The Giants will need to find a way to compensate for the loss of Barkley's production, while the Seahawks will have to protect their quarterback without their starting left tackle. It will be an interesting matchup to watch, especially with Adams returning to face his former team.